Reaction Technology

Angelini Fine Chemicals has a long tradition in API industry and has built up a comprehensive capability and expertise to carry out complex and hazardous operations for the manufacturing API and HPAPI, safely, in accordance with cGMP standards and customer quality expectations.

Among the foremost reactions routinely scaled-up and used in Aprilia plant include:

• Alkylations
• Aminations
• Asymetric Reactions
• Chlorinations and halide exchange
• Condensations
• Cross-Coupling reactions
• Dehydrogenation
• Diazotations
• Esterifications
• Friedel-Crafts Reactions
• Grignard Reactions
• Halogenations
• High-pressure Reactions
• High-temeperature reactions (up to 250°C)
• Hydrazine chemistry
• Hydrations
• Hydrogen peroxide chemistry (metal catalyst)
• Hydrogen Transfer reactions
• Hydrogenations
• Isomerizations
• Microreactions / Continuous flow technology
• Nitrations
• Optical resolution
• Organometallic Reactions
• Oxidations
• Reductions
• Ring closure and aromatisation
• Silylation
• Solvent free reaction (net condition)

Reaction technology is supported and reinforced by a continuous programme of investment in R&D and novel chemical technologies, leading to significant process innovation and intensification.